Activity record

PGDB_A000563

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetVAV1
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000190
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031694
Compound IDPGDB_C031694
Compound化合物 126
Source record IDPGDB_C031694
InChIKeyWTIRZHNTVKEIRN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000190
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Detection targetprotein_degradation
TargetVAV1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物 126

化合物 126 enlarged structure化合物 126 location on patent page 153
Activity table
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