Activity record

PGDB_A000564

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 25.8 nM

E3 ligaseCRBN
Cell lineLS513
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001452
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031951
Compound IDPGDB_C031951
CompoundI-11;I-11
Source record IDPGDB_C031951
InChIKeyBKFJTIPOMHWJEY-NRXZYEDZSA-N

Assay context

Assay IDPGDB_AS001452
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLS513
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-11;I-11

I-11;I-11 enlarged structureI-11;I-11 location on patent page 249
Activity table
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