Activity record

PGDB_A000593

Assay: % DegradationTarget: KRASQC: standardized
Activity overview

DC50 = 9.8 nM

TargetKRAS
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002526
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031954
Compound IDPGDB_C031954
CompoundI-14;I-14
Source record IDPGDB_C031954
InChIKeyZJVJHHJRNMBREP-JMWSJCINSA-N

Assay context

Assay IDPGDB_AS002526
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-14;I-14

I-14;I-14 enlarged structureI-14;I-14 location on patent page 249
Activity table
Page 287 · table start
Page 288 · table end