Activity record

PGDB_A000606

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 < 100 nM

TargetVAV1
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001875
PatentWO2026119245A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C032164
Compound IDPGDB_C032164
Compound117
Source record IDPGDB_C032164
InChIKeyPMYADRAYCDOICS-RUZDIDTESA-N

Assay context

Assay IDPGDB_AS001875
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Detection targetprotein_degradation
TargetVAV1
E3Not specified

Source evidence

Patent IDWO2026119245A1
Compound location

117

117 enlarged structure117 location on patent page 54
Activity table
Page 64 · table start
Page 65 · table middle
Page 66 · table end