Activity record

PGDB_A000696

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

Dmax = 77 %

TargetKRAS
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001980
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031963
Compound IDPGDB_C031963
CompoundI-23
Source record IDPGDB_C031963
InChIKeyKODIQUYYMUAFTC-WTGCYTDFSA-N

Assay context

Assay IDPGDB_AS001980
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-23

I-23 enlarged structureI-23 location on patent page 251
Activity table
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