Activity record

PGDB_A000727

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

DC50 = 14 nM

TargetKRAS
Time18 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001045
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031966
Compound IDPGDB_C031966
CompoundI-26
Source record IDPGDB_C031966
InChIKeyJJWUBVBMDJODMV-QDEQVNOOSA-N

Assay context

Assay IDPGDB_AS001045
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-26

I-26 enlarged structureI-26 location on patent page 252
Activity table
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