Activity record

PGDB_A000756

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 3.8 nM

TargetVAV1
Cell line293T-VAV1-FLAG
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000831
PatentWO2026103873A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031427
Compound IDPGDB_C031427
Compound85;85;化合物85
Source record IDPGDB_C031427
InChIKeyBWMRUAHCBIVRGR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000831
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell line293T-VAV1-FLAG
OrganismHomo sapiens

Source evidence

Patent IDWO2026103873A1
Compound location

85;85;化合物85

85;85;化合物85 enlarged structure85;85;化合物85 location on patent page 12
Activity table
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