Activity record

PGDB_A001228

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

DC50 = 104 nM

TargetNEK7
Cell lineCAL-51
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000897
PatentWO2026099466A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031244
Compound IDPGDB_C031244
Compound46
Source record IDPGDB_C031244
InChIKeyCGVCYRBNCSCPSX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000897
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2026099466A1
Compound location

46

46 enlarged structure46 location on patent page 54
Activity table
Page 186 · table start
Page 187 · table end