Activity record

PGDB_A001278

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 = 2.2 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS002171
PatentWO2026099466A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031275
Compound IDPGDB_C031275
Compound77
Source record IDPGDB_C031275
InChIKeyDSHKEHGIFBRVCO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002171
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2026099466A1
Compound location

77

77 enlarged structure77 location on patent page 56
Activity table
Page 186 · table start
Page 187 · table end