Assay

PGDB_AS002171

System: biochemicalTarget: CRBN
Assay context summary

Assay context

130 activity records
Assay familybiochemical
Systembiochemical
ReadoutEC50
TargetCRBN
E3CRBN
TechnologyHTRF
Activity compounds and values

Activity records

130 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C031256
EC50-=1.2uM-—CRBNCRBN-WO2026099466A1PGDB_A000010PGDB_C031256PGDB_AS002171View
2D structure for PGDB_C031289
EC50-=2.7uM-—CRBNCRBN-WO2026099466A1PGDB_A000019PGDB_C031289PGDB_AS002171View
2D structure for PGDB_C031302
EC50-=1.7uM-—CRBNCRBN-WO2026099466A1PGDB_A000151PGDB_C031302PGDB_AS002171View
2D structure for PGDB_C031326
EC50-=1.8uM-—CRBNCRBN-WO2026099466A1PGDB_A000219PGDB_C031326PGDB_AS002171View
2D structure for PGDB_C031225
EC50-=3.3uM-—CRBNCRBN-WO2026099466A1PGDB_A000235PGDB_C031225PGDB_AS002171View
2D structure for PGDB_C031292
EC50-=1.2uM-—CRBNCRBN-WO2026099466A1PGDB_A000242PGDB_C031292PGDB_AS002171View
2D structure for PGDB_C031299
EC50-=1.9uM-—CRBNCRBN-WO2026099466A1PGDB_A000352PGDB_C031299PGDB_AS002171View
2D structure for PGDB_C031228
EC50-=1.4uM-—CRBNCRBN-WO2026099466A1PGDB_A000453PGDB_C031228PGDB_AS002171View
2D structure for PGDB_C031314
EC50-=2.4uM-—CRBNCRBN-WO2026099466A1PGDB_A000688PGDB_C031314PGDB_AS002171View
2D structure for PGDB_C031216
EC50-=4.3uM-—CRBNCRBN-WO2026099466A1PGDB_A000788PGDB_C031216PGDB_AS002171View
2D structure for PGDB_C031201
EC50-=2.8uM-—CRBNCRBN-WO2026099466A1PGDB_A000816PGDB_C031201PGDB_AS002171View
2D structure for PGDB_C031206
EC50-=2.3uM-—CRBNCRBN-WO2026099466A1PGDB_A000931PGDB_C031206PGDB_AS002171View
2D structure for PGDB_C031222
EC50-=3.1uM-—CRBNCRBN-WO2026099466A1PGDB_A000970PGDB_C031222PGDB_AS002171View
2D structure for PGDB_C031227
EC50-=1.3uM-—CRBNCRBN-WO2026099466A1PGDB_A000976PGDB_C031227PGDB_AS002171View
2D structure for PGDB_C031230
EC50-=3.4uM-—CRBNCRBN-WO2026099466A1PGDB_A001028PGDB_C031230PGDB_AS002171View
2D structure for PGDB_C031214
EC50-=1.5uM-—CRBNCRBN-WO2026099466A1PGDB_A001079PGDB_C031214PGDB_AS002171View
2D structure for PGDB_C031278
EC50-=1.6uM-—CRBNCRBN-WO2026099466A1PGDB_A001170PGDB_C031278PGDB_AS002171View
2D structure for PGDB_C031275
EC50-=2.2uM-—CRBNCRBN-WO2026099466A1PGDB_A001278PGDB_C031275PGDB_AS002171View
2D structure for PGDB_C031321
EC50-=1.5uM-—CRBNCRBN-WO2026099466A1PGDB_A001313PGDB_C031321PGDB_AS002171View
2D structure for PGDB_C031323
EC50-=5.8uM-—CRBNCRBN-WO2026099466A1PGDB_A001343PGDB_C031323PGDB_AS002171View
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