Activity record

PGDB_A001297

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

Dmax = 82 %

TargetKRAS
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001227
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031991
Compound IDPGDB_C031991
CompoundI-52;I-52
Source record IDPGDB_C031991
InChIKeyOXRIXLHCDCISSI-SORUKZJLSA-N

Assay context

Assay IDPGDB_AS001227
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-52;I-52

I-52;I-52 enlarged structureI-52;I-52 location on patent page 284
Activity table
Page 287 · table start
Page 288 · table end