Activity record

PGDB_A001381

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

IC50 = 21.55 nM

TargetVAV1
Time24 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000533
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031198
Compound IDPGDB_C031198
Compound对照化合物 1
Source record IDPGDB_C031787
InChIKeyRIFDPWJLHNZGEX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000533
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time24 h
TargetVAV1
E3Not specified
Organismcanine

Source evidence

Patent IDWO2026114367A1
Compound location

对照化合物 1

对照化合物 1 enlarged structure对照化合物 1 location on patent page 209
Activity table
Page 208 · table single