Activity record

PGDB_A001441

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

DC50 = 37 nM

TargetNEK7
Cell lineCAL-51
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000897
PatentWO2026099466A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031269
Compound IDPGDB_C031269
Compound71
Source record IDPGDB_C031269
InChIKeyHFPQCFDHYBXVHV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000897
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2026099466A1
Compound location

71

71 enlarged structure71 location on patent page 55
Activity table
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