Activity record

PGDB_A001453

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetVAV1
Cell lineprimary_human_blood
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001692
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031684
Compound IDPGDB_C031684
Compound化合物101
Source record IDPGDB_C031684
InChIKeyZGGGZZDWZUXQQS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001692
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TargetVAV1
E3Not specified
Cell lineprimary_human_blood
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物101

化合物101 enlarged structure化合物101 location on patent page 139
Activity table
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