Activity record

PGDB_A002046

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 26.47 nM

TargetVAV1
Cell line293T-VAV1-FLAG
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000831
PatentWO2026103873A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031445
Compound IDPGDB_C031445
Compound134;134;134
Source record IDPGDB_C031445
InChIKeyNAXCKIISLVQADA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000831
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell line293T-VAV1-FLAG
OrganismHomo sapiens

Source evidence

Patent IDWO2026103873A1
Compound location

134;134;134

134;134;134 enlarged structure134;134;134 location on patent page 13
Activity table
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