Activity record

PGDB_A002488

Assay: % DegradationTarget: VAV1QC: standardized
Activity overview

Dmax = 84.2 %

TargetVAV1
Cell lineJurkat
Concentration0.08 nM
Assay / ReadoutHTRF / Dmax
Assay IDPGDB_AS000246
PatentWO2026119120A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C032001
Compound IDPGDB_C032001
Compound1;1;1
Source record IDPGDB_C032001
InChIKeyRZHZTOIBUYOFNZ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000246
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TechnologyHTRF
Concentration0.08 nM
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026119120A1
Compound location

1;1;1

1;1;1 enlarged structure1;1;1 location on patent page 26
Activity table
Page 122 · table single