Activity record

PGDB_A002575

Assay: viabilityTarget: VAV1QC: standardized
Activity overview

IC50 = 2.21 nM

TargetVAV1
Cell lineREC-1
Time120 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000941
PatentWO2026103798A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031365
Compound IDPGDB_C031365
Compound实施例46
Source record IDPGDB_C031365
InChIKeyMTYHGTVEOZDOAY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000941
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time120 h
Detection target% Cell viability
TargetVAV1
E3Not specified
Cell lineREC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2026103798A1
Compound location

实施例46

实施例46 enlarged structure实施例46 location on patent page 77
Activity table
Page 88 · table single