Activity record

PGDB_A002618

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

DC50 = 21.87761623949552 nM

TargetCDK2
Cell lineHEK293T
Time6-hour
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001728
PatentWO2026064643A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030651
Compound IDPGDB_C030651
Compound2
Source record IDPGDB_C030651
InChIKeyRKXDIPZBCZCEBP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001728
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time6-hour
TargetCDK2
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2026064643A1
Compound location

2

2 enlarged structure2 location on patent page 109
Activity table
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