PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2026064643A1

AssigneePlexium

TitleCompounds, compositions, and methods of use thereof

Family IDunresolved_family_WO2026064643A1

Family members1

Filing year2025

Publication date2026-03-26

JurisdictionWO

Compounds10

Activity records20

Assays2

Activity compounds and values

Activity records

20 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	=	12.02264434617413	nM	-	—	CDK2	-	HEK293T	PGDB_A000290	PGDB_C011110	PGDB_AS001728	View
DC50	-	=	66.06934480075964	nM	-	—	CDK2	-	HEK293T	PGDB_A000319	PGDB_C011112	PGDB_AS001728	View
DC50	-	=	3.019951720402019	nM	-	—	CDK2	-	HEK293T	PGDB_A001507	PGDB_C030652	PGDB_AS001728	View
DC50	-	=	21.87761623949552	nM	-	—	CDK2	-	HEK293T	PGDB_A002618	PGDB_C030651	PGDB_AS001728	View
Dmax	-	=	59.6	%	10 uM	-	CDK2	-	HEK293T	PGDB_A004323	PGDB_C030651	PGDB_AS000752	View
Dmax	-	=	49.2	%	10 uM	-	CDK2	-	HEK293T	PGDB_A004371	PGDB_C011112	PGDB_AS000752	View
Dmax	-	=	56.9	%	10 uM	-	CDK2	-	HEK293T	PGDB_A004500	PGDB_C026003	PGDB_AS000752	View
Dmax	-	=	75.4	%	10 uM	-	CDK2	-	HEK293T	PGDB_A005351	PGDB_C030654	PGDB_AS000752	View
DC50	-	=	10	nM	-	—	CDK2	-	HEK293T	PGDB_A005853	PGDB_C026003	PGDB_AS001728	View
Dmax	-	=	80.7	%	10 uM	-	CDK2	-	HEK293T	PGDB_A005858	PGDB_C030652	PGDB_AS000752	View
DC50	-	=	0.3235936569296281	nM	-	—	CDK2	-	HEK293T	PGDB_A006684	PGDB_C030654	PGDB_AS001728	View
Dmax	-	=	67	%	10 uM	-	CDK2	-	HEK293T	PGDB_A078294	PGDB_C025999	PGDB_AS000752	View
DC50	-	=	3.019951720402019	nM	-	—	CDK2	-	HEK293T	PGDB_A078614	PGDB_C025999	PGDB_AS001728	View
Dmax	-	=	67.3	%	10 uM	-	CDK2	-	HEK293T	PGDB_A079434	PGDB_C011110	PGDB_AS000752	View
DC50	-	=	28.18382931264455	nM	-	—	CDK2	-	HEK293T	PGDB_A079634	PGDB_C026001	PGDB_AS001728	View
Dmax	-	=	71.1	%	10 uM	-	CDK2	-	HEK293T	PGDB_A079705	PGDB_C030653	PGDB_AS000752	View
Dmax	-	=	58.7	%	10 uM	-	CDK2	-	HEK293T	PGDB_A080009	PGDB_C030650	PGDB_AS000752	View
Dmax	-	=	33	%	10 uM	-	CDK2	-	HEK293T	PGDB_A080083	PGDB_C026001	PGDB_AS000752	View
DC50	-	=	3.981071705534969	nM	-	—	CDK2	-	HEK293T	PGDB_A080552	PGDB_C030653	PGDB_AS001728	View
DC50	-	=	32.35936569296281	nM	-	—	CDK2	-	HEK293T	PGDB_A080789	PGDB_C030650	PGDB_AS001728	View

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