Activity record

PGDB_A002696

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetVAV1
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000190
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031716
Compound IDPGDB_C031716
Compound104-2
Source record IDPGDB_C031716
InChIKeyVMDHIUBRBGRAMC-UCLFCPHBSA-N

Assay context

Assay IDPGDB_AS000190
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Detection targetprotein_degradation
TargetVAV1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

104-2

104-2 enlarged structure104-2 location on patent page 142
Activity table
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