Activity record

PGDB_A003002

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

DC50 = 2 nM

TargetKRAS
Time18 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001045
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031977
Compound IDPGDB_C031977
CompoundI-38;I-38
Source record IDPGDB_C031977
InChIKeyBTNNHERGHYOQCF-DATZMYEBSA-N

Assay context

Assay IDPGDB_AS001045
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-38;I-38

I-38;I-38 enlarged structureI-38;I-38 location on patent page 269
Activity table
Page 287 · table start
Page 288 · table end