Activity record

PGDB_A003147

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 22.2 nM

E3 ligaseCRBN
Cell lineSW1990
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000509
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031952
Compound IDPGDB_C031952
CompoundI-12;I-12
Source record IDPGDB_C031952
InChIKeyBKFJTIPOMHWJEY-MSYDMZQYSA-N

Assay context

Assay IDPGDB_AS000509
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSW1990
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-12;I-12

I-12;I-12 enlarged structureI-12;I-12 location on patent page 249
Activity table
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