Activity record

PGDB_A003251

Assay: viabilityTarget: VAV1QC: ambiguous
Activity overview

IC50 <= 1 nM

TargetVAV1
Cell lineprimaryT
Time24 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000152
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031773
Compound IDPGDB_C031773
Compound化合物81
Source record IDPGDB_C031773
InChIKeyIWYKUFAKTFJTJA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000152
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time24 h
TargetVAV1
E3Not specified
Cell lineprimaryT
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物81

化合物81 enlarged structure化合物81 location on patent page 129
Activity table
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