Activity record

PGDB_A003501

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetVAV1
Time24 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000052
PatentWO2026114368A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031891
Compound IDPGDB_C031891
Compound63
Source record IDPGDB_C031891
InChIKeyPPEBNLPEEHNPFU-PYUWXLGESA-N

Assay context

Assay IDPGDB_AS000052
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time24 h
Detection targetprotein_degradation
TargetVAV1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114368A1
Compound location

63

63 enlarged structure63 location on patent page 92
Activity table
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