Activity record

PGDB_A003697

Assay: % DegradationTarget: KRASQC: standardized
Activity overview

DC50 = 2.8 nM

TargetKRAS
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002526
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031962
Compound IDPGDB_C031962
CompoundI-22;I-22
Source record IDPGDB_C031962
InChIKeyYFISPOBZWQPMEZ-HXLDEWOPSA-N

Assay context

Assay IDPGDB_AS002526
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-22;I-22

I-22;I-22 enlarged structureI-22;I-22 location on patent page 251
Activity table
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