Activity record

PGDB_A004243

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 373.1 nM

TargetKRAS
Cell lineLS513
Time120 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002012
PatentWO2026114957A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031939
Compound IDPGDB_C031939
CompoundI-1;I-1;I-1
Source record IDPGDB_C031939
InChIKeyOMHBONXEUVXOQU-BGASMWSGSA-N

Assay context

Assay IDPGDB_AS002012
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time120 h
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineLS513
OrganismHomo sapiens

Source evidence

Patent IDWO2026114957A1
Compound location

I-1;I-1;I-1

I-1;I-1;I-1 enlarged structureI-1;I-1;I-1 location on patent page 145
Activity table
Page 163 · table single