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Compound
PGDB_C031939
4 activity records1 related patents
2D structure
C[C@H](Oc1nc(-c2noc3c2CCC[C@@]32CCCc3sc(N)c(C#N)c32)nc2c1CN(C(=O)CN1CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC1)C2)[C@@H]1CCCN1CCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 16.3 | nM | - | — | KRAS | - | SW1990 | WO2026114957A1 | PGDB_A001800 | PGDB_C031939 | PGDB_AS002577 | View |
| IC50 | - | = | 4 | nM | - | — | KRAS | - | GP5d | WO2026114957A1 | PGDB_A003767 | PGDB_C031939 | PGDB_AS000902 | View |
| IC50 | - | = | 373.1 | nM | - | — | KRAS | - | LS513 | WO2026114957A1 | PGDB_A004243 | PGDB_C031939 | PGDB_AS002012 | View |
| IC50 | - | = | 67.8 | nM | - | — | KRAS | - | NCI-H727 | WO2026114957A1 | PGDB_A078203 | PGDB_C031939 | PGDB_AS000308 | View |