Activity record

PGDB_A004388

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 64.3 nM

E3 ligaseCRBN
Cell lineLS513
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001452
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031955
Compound IDPGDB_C031955
CompoundI-15
Source record IDPGDB_C031955
InChIKeyZJVJHHJRNMBREP-WTGCYTDFSA-N

Assay context

Assay IDPGDB_AS001452
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLS513
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-15

I-15 enlarged structureI-15 location on patent page 249
Activity table
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