Activity record

PGDB_A004535

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

Dmax = 82 %

TargetKRAS
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001980
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031993
Compound IDPGDB_C031993
CompoundI-54
Source record IDPGDB_C031993
InChIKeyOZYRFVZGGPFHHY-MYPZJTEESA-N

Assay context

Assay IDPGDB_AS001980
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-54

I-54 enlarged structureI-54 location on patent page 284
Activity table
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