Activity record

PGDB_A004824

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 20-30 %

TargetCRBN
E3 ligaseCRBN
Concentration0.5 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS000662
PatentWO2026061475A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030310
Compound IDPGDB_C030310
CompoundGT-09581
Source record IDPGDB_C030310
InChIKeySTGSEAPQLWZROE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000662
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration0.5 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2026061475A1
Compound location

GT-09581

GT-09581 enlarged structureGT-09581 location on patent page 83
Activity table
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