Assay

PGDB_AS000662

System: cell_basedTarget: CRBN
Assay context summary

Assay context

210 activity records
Assay familybiochemical
Systemcell_based
Readout% Inhibition
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Detection targetcell_inhibition
Activity compounds and values

Activity records

210 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C030500
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000021PGDB_C030500PGDB_AS000662View
2D structure for PGDB_C030285
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000024PGDB_C030285PGDB_AS000662View
2D structure for PGDB_C030485
% Inhibition-=10-20%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000084PGDB_C030485PGDB_AS000662View
2D structure for PGDB_C030542
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000164PGDB_C030542PGDB_AS000662View
2D structure for PGDB_C030463
% Inhibition-=30-40%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000285PGDB_C030463PGDB_AS000662View
2D structure for PGDB_C030445
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000304PGDB_C030445PGDB_AS000662View
2D structure for PGDB_C030455
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000313PGDB_C030455PGDB_AS000662View
2D structure for PGDB_C030372
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000354PGDB_C030372PGDB_AS000662View
2D structure for PGDB_C030466
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000424PGDB_C030466PGDB_AS000662View
2D structure for PGDB_C030492
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000473PGDB_C030492PGDB_AS000662View
2D structure for PGDB_C030409
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000475PGDB_C030409PGDB_AS000662View
2D structure for PGDB_C030479
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000515PGDB_C030479PGDB_AS000662View
2D structure for PGDB_C030287
% Inhibition-=53-60%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000532PGDB_C030287PGDB_AS000662View
2D structure for PGDB_C030487
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000607PGDB_C030487PGDB_AS000662View
2D structure for PGDB_C030451
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000628PGDB_C030451PGDB_AS000662View
2D structure for PGDB_C030448
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000752PGDB_C030448PGDB_AS000662View
2D structure for PGDB_C030528
% Inhibition-=60-70%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000828PGDB_C030528PGDB_AS000662View
2D structure for PGDB_C030453
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000895PGDB_C030453PGDB_AS000662View
2D structure for PGDB_C030495
% Inhibition-=40-53%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000899PGDB_C030495PGDB_AS000662View
2D structure for PGDB_C030537
% Inhibition-=20-30%0.5 uM-CRBNCRBN-WO2026061475A1PGDB_A000919PGDB_C030537PGDB_AS000662View
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