Activity record

PGDB_A005056

Assay: viabilityTarget: VAV1QC: ambiguous
Activity overview

IC50 <= 1 nM

TargetVAV1
Cell lineprimaryT
Time96 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002534
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031773
Compound IDPGDB_C031773
Compound化合物81
Source record IDPGDB_C031773
InChIKeyIWYKUFAKTFJTJA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002534
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time96 h
Detection target% Cell viability
TargetVAV1
E3Not specified
Cell lineprimaryT
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物81

化合物81 enlarged structure化合物81 location on patent page 129
Activity table
Page 207 · table single