Activity record

PGDB_A005133

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 2.6 nM

E3 ligaseCRBN
Cell lineGP5d
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS002003
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031985
Compound IDPGDB_C031985
CompoundI-46;I-46
Source record IDPGDB_C031985
InChIKeyDDLJVSSBHUDEEC-VKZCRJDXSA-N

Assay context

Assay IDPGDB_AS002003
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineGP5d
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-46;I-46

I-46;I-46 enlarged structureI-46;I-46 location on patent page 282
Activity table
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