Activity record

PGDB_A005300

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 57.3 nM

E3 ligaseCRBN
Cell lineSW1990
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000509
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031976
Compound IDPGDB_C031976
CompoundI-37;I-37
Source record IDPGDB_C031976
InChIKeyKGWYXOVJAHNVRU-ZUTXJMHQSA-N

Assay context

Assay IDPGDB_AS000509
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSW1990
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-37;I-37

I-37;I-37 enlarged structureI-37;I-37 location on patent page 267
Activity table
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