Activity record

PGDB_A005351

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 75.4 %

TargetCDK2
Cell lineHEK293T
Concentration10 uM
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000752
PatentWO2026064643A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030654
Compound IDPGDB_C030654
Compound5;Ex 5
Source record IDPGDB_C030654
InChIKeyGTIRPFRCUKUZKU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000752
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
TargetCDK2
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2026064643A1
Compound location

5;Ex 5

5;Ex 5 enlarged structure5;Ex 5 location on patent page 113
Activity table
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