Activity record

PGDB_A005460

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

Dmax = 70 %

TargetKRAS
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001980
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031984
Compound IDPGDB_C031984
CompoundI-45;I-45
Source record IDPGDB_C031984
InChIKeyYGDBEDORGSHSCK-CRWRIZQQSA-N

Assay context

Assay IDPGDB_AS001980
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-45;I-45

I-45;I-45 enlarged structureI-45;I-45 location on patent page 282
Activity table
Page 287 · table start
Page 288 · table end