Activity record

PGDB_A005747

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 62 nM

TargetCRBN
E3 ligaseCRBN
Cell lineTni(Hi5)insect
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS000132
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031995
Compound IDPGDB_C031995
CompoundI-56;I-56
Source record IDPGDB_C031995
InChIKeyUYOAOCCUFXHJIB-CLCJOLLWSA-N

Assay context

Assay IDPGDB_AS000132
Assay familybinding
Assay systemcell_based
ReadoutIC50
TargetCRBN
E3CRBN
Cell lineTni(Hi5)insect
Organisminsect cells

Source evidence

Patent IDWO2026114958A1
Compound location

I-56;I-56

I-56;I-56 enlarged structureI-56;I-56 location on patent page 284
Activity table
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