Assay

PGDB_AS000132

System: cell_basedTarget: CRBNCell line: Tni(Hi5)insect
Assay context summary

Assay context

58 activity records
Assay familybinding
Systemcell_based
ReadoutIC50
TargetCRBN
E3CRBN
Cell lineTni(Hi5)insect
Organisminsect cells
Activity compounds and values

Activity records

58 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C031957
IC50-=138nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A000239PGDB_C031957PGDB_AS000132View
2D structure for PGDB_C031961
IC50-=535nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A000585PGDB_C031961PGDB_AS000132View
2D structure for PGDB_C031946
IC50-=195nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A000956PGDB_C031946PGDB_AS000132View
2D structure for PGDB_C031953
IC50-=593nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A001189PGDB_C031953PGDB_AS000132View
2D structure for PGDB_C031941
IC50-=478nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A001496PGDB_C031941PGDB_AS000132View
2D structure for PGDB_C031943
IC50-=387nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A001620PGDB_C031943PGDB_AS000132View
2D structure for PGDB_C031949
IC50-=1038nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A001982PGDB_C031949PGDB_AS000132View
2D structure for PGDB_C031972
IC50-=95nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A002032PGDB_C031972PGDB_AS000132View
2D structure for PGDB_C031993
IC50-=102nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A002060PGDB_C031993PGDB_AS000132View
2D structure for PGDB_C031969
IC50-=466nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A002148PGDB_C031969PGDB_AS000132View
2D structure for PGDB_C031944
IC50-=489nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A002172PGDB_C031944PGDB_AS000132View
2D structure for PGDB_C031951
IC50-=877nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A002240PGDB_C031951PGDB_AS000132View
2D structure for PGDB_C031968
IC50-=88nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A002665PGDB_C031968PGDB_AS000132View
2D structure for PGDB_C031992
IC50-=607nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A003105PGDB_C031992PGDB_AS000132View
2D structure for PGDB_C031988
IC50-=139nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A003306PGDB_C031988PGDB_AS000132View
2D structure for PGDB_C031948
IC50-=179nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A003353PGDB_C031948PGDB_AS000132View
2D structure for PGDB_C031970
IC50-=72nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A003470PGDB_C031970PGDB_AS000132View
2D structure for PGDB_C031964
IC50-=617nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A003958PGDB_C031964PGDB_AS000132View
2D structure for PGDB_C031959
IC50-=424nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A004024PGDB_C031959PGDB_AS000132View
2D structure for PGDB_C031950
IC50-=168nM-—CRBNCRBNTni(Hi5)insectWO2026114958A1PGDB_A004027PGDB_C031950PGDB_AS000132View
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