Activity record

PGDB_A005961

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

degradation < 25 %

TargetVAV1
Cell lineJurkat
Concentration1 nM
Assay / Readout% Degradation
Assay IDPGDB_AS001791
PatentWO2026061428A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011096
Compound IDPGDB_C011096
Compound1
Source record IDPGDB_C030142
InChIKeyOKRVMFXYEUUGRJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001791
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration1 nM
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026061428A1
Activity table
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