Activity record

PGDB_A005991

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 0.84 nM

TargetVAV1
Cell line293T-VAV1-FLAG
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000831
PatentWO2026103873A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031404
Compound IDPGDB_C031404
Compound33;33;化合物 33
Source record IDPGDB_C031404
InChIKeySGMLTPSQDHPSRL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000831
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell line293T-VAV1-FLAG
OrganismHomo sapiens

Source evidence

Patent IDWO2026103873A1
Compound location

33;33;化合物 33

33;33;化合物 33 enlarged structure33;33;化合物 33 location on patent page 11
Activity table
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