Activity record

PGDB_A006047

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

degradation = 25-75 %

TargetVAV1
Cell lineJurkat
Concentration100 nM
Assay / Readout% Degradation
Assay IDPGDB_AS000798
PatentWO2026061428A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011097
Compound IDPGDB_C011097
Compound2
Source record IDPGDB_C030143
InChIKeyCOOQOKCWUTVQPQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000798
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration100 nM
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026061428A1
Activity table
Page 368 · table single