Activity record

PGDB_A006254

Assay: % DegradationTarget: KRASQC: standardized
Activity overview

DC50 = 4.7 nM

TargetKRAS
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002526
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031996
Compound IDPGDB_C031996
CompoundI-57
Source record IDPGDB_C031996
InChIKeyDQANNJLPOFMOFU-FDEWETLASA-N

Assay context

Assay IDPGDB_AS002526
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-57

I-57 enlarged structureI-57 location on patent page 348
Activity table
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