Activity record

PGDB_A006357

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

Dmax = 78 %

TargetKRAS
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001227
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031957
Compound IDPGDB_C031957
CompoundI-17;I-17
Source record IDPGDB_C031957
InChIKeyNFNDLOABGSRXDS-JLEXMSBSSA-N

Assay context

Assay IDPGDB_AS001227
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-17;I-17

I-17;I-17 enlarged structureI-17;I-17 location on patent page 250
Activity table
Page 287 · table start
Page 288 · table end