Activity record

PGDB_A006521

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

DC50 = 2.7 nM

TargetKRAS
Time18 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001045
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031986
Compound IDPGDB_C031986
CompoundI-47;I-47
Source record IDPGDB_C031986
InChIKeyJYZLLAVPNYLUCZ-BIRUVABTSA-N

Assay context

Assay IDPGDB_AS001045
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-47;I-47

I-47;I-47 enlarged structureI-47;I-47 location on patent page 283
Activity table
Page 287 · table start
Page 288 · table end