Activity record

PGDB_A006684

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

DC50 = 0.3235936569296281 nM

TargetCDK2
Cell lineHEK293T
Time6-hour
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001728
PatentWO2026064643A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030654
Compound IDPGDB_C030654
Compound5;Ex 5
Source record IDPGDB_C030654
InChIKeyGTIRPFRCUKUZKU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001728
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time6-hour
TargetCDK2
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2026064643A1
Compound location

5;Ex 5

5;Ex 5 enlarged structure5;Ex 5 location on patent page 113
Activity table
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