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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A007086

Assay: % DegradationQC: standardized

Activity overview

DC50 > 10000 nM

Cell lineNCI-H929.11

TimeDC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM

Assay / Readoutluminescence / DC50

Assay IDPGDB_AS000877

PatentWO2022081927A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C016632

Compound60

Source record IDPGDB_C026761

InChIKeyDEIHHMLDBOYXDV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000877

Assay family% Degradation

Assay systemcell_based

ReadoutDC50

Technologyluminescence

Treatment timeDC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM

TargetIKZF1

E3Not specified

Cell lineNCI-H929.11

Source evidence

Patent IDWO2022081927A1

Compound location

60

60 enlarged structure

60 location on patent page 529

Activity table

Page 529 · table start

Page 530 · table middle

Page 531 · table middle

Page 532 · table middle

Page 533 · table middle

Page 534 · table middle

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU