Activity record

PGDB_A007221

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 1-10 uM

TargetCRBN
E3 ligaseCRBN
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001252
PatentWO2022066835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019559
Compound IDPGDB_C019559
Compound9
Source record IDPGDB_C001369
InChIKeyLZUFJJLEOOPIJW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001252
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022066835A1
Compound location

9

9 enlarged structure9 location on patent page 171
Activity table
Page 165 · table single