PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2022066835A1

AssigneeSt Jude Childrens Research Hospital

TitleSubstituted n-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)arylsulfonamide analogs as modulators of cereblon protein

Family ID80845797

Family members20

Filing year2021

Publication date2022-03-31

JurisdictionWO

Compounds88

Activity records97

Assays2

Activity compounds and values

Activity records

97 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A007221	PGDB_C019559	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A007339	PGDB_C019589	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A008030	PGDB_C019578	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A009243	PGDB_C019572	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A010760	PGDB_C001432	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A010778	PGDB_C019582	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A011027	PGDB_C019590	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A011695	PGDB_C001390	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A012858	PGDB_C001419	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A013128	PGDB_C001411	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A013177	PGDB_C001422	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A013289	PGDB_C001387	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A013546	PGDB_C019592	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A013806	PGDB_C001426	PGDB_AS001252	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A014057	PGDB_C019587	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A014213	PGDB_C001363	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A014616	PGDB_C019590	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A014743	PGDB_C001397	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A014870	PGDB_C001391	PGDB_AS001252	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A015298	PGDB_C019575	PGDB_AS001252	View

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