Assay

PGDB_AS001252

System: biochemicalTarget: CRBN
Assay context summary

Assay context

90 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Technologyfluorescence
Activity compounds and values

Activity records

90 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C019559
IC50-=1-10uM-—CRBNCRBN-WO2022066835A1PGDB_A007221PGDB_C019559PGDB_AS001252View
2D structure for PGDB_C019589
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A007339PGDB_C019589PGDB_AS001252View
2D structure for PGDB_C019578
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A008030PGDB_C019578PGDB_AS001252View
2D structure for PGDB_C019572
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A009243PGDB_C019572PGDB_AS001252View
2D structure for PGDB_C001432
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A010760PGDB_C001432PGDB_AS001252View
2D structure for PGDB_C019582
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A010778PGDB_C019582PGDB_AS001252View
2D structure for PGDB_C019590
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A011027PGDB_C019590PGDB_AS001252View
2D structure for PGDB_C001390
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A011695PGDB_C001390PGDB_AS001252View
2D structure for PGDB_C001419
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A012858PGDB_C001419PGDB_AS001252View
2D structure for PGDB_C001411
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A013128PGDB_C001411PGDB_AS001252View
2D structure for PGDB_C001422
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A013177PGDB_C001422PGDB_AS001252View
2D structure for PGDB_C001387
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A013289PGDB_C001387PGDB_AS001252View
2D structure for PGDB_C019592
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A013546PGDB_C019592PGDB_AS001252View
2D structure for PGDB_C001426
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A013806PGDB_C001426PGDB_AS001252View
2D structure for PGDB_C019587
IC50-=1-10uM-—CRBNCRBN-WO2022066835A1PGDB_A014057PGDB_C019587PGDB_AS001252View
2D structure for PGDB_C001363
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A014213PGDB_C001363PGDB_AS001252View
2D structure for PGDB_C019590
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A014616PGDB_C019590PGDB_AS001252View
2D structure for PGDB_C001397
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A014743PGDB_C001397PGDB_AS001252View
2D structure for PGDB_C001391
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A014870PGDB_C001391PGDB_AS001252View
2D structure for PGDB_C019575
IC50-<1uM-—CRBNCRBN-WO2022066835A1PGDB_A015298PGDB_C019575PGDB_AS001252View
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