Activity record

PGDB_A007222

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

EC50 = 253 nM

TargetGSPT1
Cell lineHEK293
Time72 h
Assay / Readoutluminescence / EC50
Assay IDPGDB_AS002492
PatentIL323841A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008163
Compound IDPGDB_C008163
Compound12
Source record IDPGDB_C008163
InChIKeyAOUHKTNYEATNJX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002492
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyluminescence
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDIL323841A
Compound location

12

12 enlarged structure12 location on patent page 53
Activity table
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